Maintenance Plasma Exchange for Neuromyelitis Optica

Overview

About this study

Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system that is associated with autoantibodies to aquaporin-4. Treatment options for prevention of clinical relapses of NMO include immunosuppressive medications. Plasma exchange (PLEX) is commonly used as a rescue therapy for NMO relapses but ongoing, regular PLEX procedures (maintenance PLEX) is sometimes used to prevent relapses. This observational registry will record feasibility, tolerability, safety, and preliminary efficacy data regarding maintenance PLEX for NMO.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Neuromyelitis optica
Neuromyelitis optica spectrum disorder
Recurrent idiopathic longitudinally extensive myelitis
Age 18 years or greater

Exclusion Criteria:

Any condition that in the opinion of the investigator could increase a participant's risk by participating in the observational study or confound the outcome of the study

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Dean Wingerchuk, M.D.	Closed for enrollment	Contact information: Irene Galasky R.N.
Rochester, Minn. Mayo Clinic principal investigator Dean Wingerchuk, M.D.	Closed for enrollment	Contact information: Delana Weis CCRP (507)266-7196 weis.delana@mayo.edu

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Dean Wingerchuk, M.D.

Closed for enrollment

Contact information:

Irene Galasky R.N.

Rochester, Minn.

Mayo Clinic principal investigator

Dean Wingerchuk, M.D.

Closed for enrollment

Contact information:

Delana Weis CCRP

(507)266-7196

weis.delana@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials