Esophageal Absorption in EoE

Overview

About this study

To determine how the esophagus in active and inactive stages of eosinophilic esophagitis transmit fluids.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study
endoscopy with esophageal and duodenal biopsies within two weeks of performance of this study
Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study, and are now in histologic remission( <15phf) by the use of steroids or the six food elimination diet.
Volunteers will be selected for not having any history of esophageal symptoms

Exclusion Criteria:

Vulnerable populations, such as those with diminished mental acuity, will be excluded.
Patients taking Nsaids within 48 hours of the d-xylose testing
artificial sweeteners within 48 hours of the d-xylose testing
History of IBD
Currently smoking or history of smoking
History of Celiac disease
Bacterial overgrowth,
motility disorders
other diffuse small bowel diseases.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator David Katzka, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

David Katzka, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials