Sensorimotor Dysfunction in Achalasia

Overview

About this study

This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand and help direct the treatment for patients with achalasia.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Adults ages 18-90
Patients with achalasia, defined by an esophageal manometry study consistent with the diagnosis

Exclusion Criteria:

Patients with EGD or esophagram findings suggestive of pseudoachalasia
Previous history of pneumatic dilation, Heller myotomy, or botulinum toxin injection to the distal esophagus
Esophageal diameter greater than 6 cm
Previous history of upper gastrointestinal surgery
Medical conditions such as severe heart or lung disease that preclude safe performance barostat
Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Karthik Ravi, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Karthik Ravi, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials