A Study to Examine the Effects of Smoking on the Esophagus

Overview

About this study

This study is being done to determine the effects smoking has on the esophagus (swallowing tube).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion criteria:

Male patients
Between ages of 18 and 80
Either an active smoker (defined as currently smoking a half a pack a day for at least 1 year). Or non-smokers (defined as not smoking for at least a year)
Scheduled to undergo an upper endoscopy and biopsies

Exclusion Criteria:

Patients will be excluded for any history of esophageal symptoms or disease.
Use of of NSAID’s within the past 2 weeks
Use of other medications that may cause esophagitis such as:Tetracyclines (doxycycline), Fosamax ,Binosto, potassium chloride, warfarin and heparin
Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator David Katzka, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

David Katzka, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials