Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers

Overview

About this study

This laboratory study is looking at genetic mutations and environmental exposure in young patients with retinoblastoma and in their parents and young healthy unrelated volunteers. Gathering information about gene mutations and environmental exposure may help doctors learn more about the causes of retinoblastoma in young patients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Cases must meet the following criteria:
- Diagnosed with sporadic retinoblastoma (RB) on or after 07/01/2006
  - No familial retinoblastoma
- Have permission of physician to contact the parents
- Diagnosed and/or treated at a Children's Oncology Group (COG) institution or *Wills Eye Hospital
Controls must meet 1 of the following criteria:
- Mother of a child with unilateral RB
- Father of a child with bilateral RB
- Age-matched non-blood-related child if possible
Must reside in the U.S. or Canada
Must have telephone in the home
Biological parent speaks English or Spanish
Concurrent treatment on a therapeutic trial is NOT required

More information

Publications

Publications are currently not available

Clinical Trials