A Study of Environmental Effects on the Intestine Bacteria Commonly Present in Children and Adolescents with Multiple Sclerosis

Overview

About this study

The objective of this study is to understand how commensal (the living together of two organisms in a relationship that is beneficial to one and has no effect on the other) bacteria are associated with MS.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Children are eligible for this study as cases or controls if they are eligible for and enrolled in the Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis study

Exclusion Criteria

  • Patients are not eligible for study participation if
    • Antibiotics or probiotics have been used within 60 days prior to enrollment
    • Steroids have been used within 45 days prior to enrollment
    • Ongoing treatment includes any disease-modifying therapy other than glatiramer acetate or interferon
    • Disease-modifying therapy treatment agent has changed (including new agent or discontinuation) 90 days or less prior to enrollment
    • Children are not eligible to participate as pediatric controls if:
      • They are 21 years of age or older
      • Antibiotic or probiotics have been used within 60 days prior to enrollment
      • Steroids have been used within 45 days prior to enrollment

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Jan-Mendelt Tillema, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available
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CLS-20151851

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