Clinical Trials

Inclusion Criteria

• Any individual ages 18 to 65
• Women who are post-menopausal or have had a hysterectomy will be considered eligible
• A subject will be considered eligible if she has no signs or symptoms of pregnancy and meets any one of the following criteria:
  • Is ≤7 days after the start of normal menses
  • Has not had sexual intercourse since the start of last normal menses
  • Has been correctly and consistently using a reliable method of contraception
  • Is ≤7 days after spontaneous or induced abortion
  • Is within 4 weeks postpartum
  • Is fully breastfeeding (exclusively breastfeeding or the vast majority [≥85%] of feeds are breastfeeds), amenorrheic, and <6 months postpartum

Exclusion Criteria

• Individuals at risk of enteric or secondary hyperoxaluria, ie have a history of 
  • Diarrhea
  • Malabsorption (Crohn’s disease, Celiac disease, history of gastric sleeve or bypass)
  • Primary hyperoxaluria
  • Use orlistat, cholestyramine or other medications known to influence fat absorption
• Have an eGFR of below 60 mL/min/1.73m2 or a 24 hour urine oxalate level of > 0.46 mmol (the upper limit of normal per our laboratory)
• Women will be excluded if they are pregnant or could be pregnant at the time of the study
  • Women must stop the study and notify the coordinator if there is a chance they may have become pregnant during the study