A Study of Magnetic Resonance Elastography to Measure Heart Muscle Stiffness in Patients with Hypertrophic Cardiomyopathy

Overview

About this study

The purpose of this study is to use magnetic resonance elastography to assess heart muscle stiffness in patients with hypertrophic cardiomyopathy compared to normal subjects.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

Normal subjects
- Age ≥ 18 years
- Normal heart sounds
- Normal breath sounds
- Measured systolic blood pressure < 140 mm Hg
- Measured diastolic blood pressure < 90 mm Hg
Hypertrophic cardiomyopathy
- A clinically-indicated cardiac MRI ordered for evaluation of hypertrophic cardiomyopathy

Exclusion Criteria

Normal Subjects
- History of angina, coronary artery disease, heart failure, hypertension, hypertensive medication, valvular heart disease, congenital heart disease, diabetes
- Contraindications or relative contraindications to MRI scanning, namely internal defibrillators or pacemakers, cerebral aneurysm clips, severe claustrophobia, and pregnancy or suspected pregnancy (self-reported)
Hypertrophic cardiomyopathy
- History of prior myocardial infarction, myocarditis, or prior heart transplantation

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Philip Araoz, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Philip Araoz, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

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