A Study to Determine the Value of Combining PET and MRI Evaluations of Spinal Joint Pain in the Lower Back

Overview

About this study

The purpose of this study is to determine the usefulness of combining PET scan activity and MRI image biomarkers for the clinical management of spinal joint low back pain.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

Male or female patient
50-100 years of age
Has clinically suspected facetogenic low back pain
Must be considered to have at least a 60% chance of having facet joints as the major source of low back pain based on overall clinical impression
Will undergo a standardized clinical exam by an experienced physical medicine and rehabilitation clinician to confirm clinical suspicion of axial low back pain
Either unilateral or bilateral axial low back pain

Exclusion Criteria

Pregnancy
Prior lumbar back surgery
History of endovascular repair of abdominal aortic aneurysm or other postoperative change likely to introduce imaging artifact to the lumbar spine
Suspected spine infection
Known osseous metastatic or other osseous malignancy
Facet joint percutaneous treatment within the past 2 months
History of major lumbar spine trauma
Inability to provide own consent
Claustrophobia, cardiac pacemaker/wires in place, any absolute contraindication to MRI
Impaired renal function indicated by a GFR less than 30
Gadolinium allergy
Highly radiosensitive medical conditions
Unable to lay quietly for 60 minutes of imaging

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Vance Lehman, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Vance Lehman, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

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