A Study of the Biological Characteristics of Lupus

Overview

About this study

The purpose of this study is to understand the characteristics associated with lupus, to assist the early development of new treatments for human lupus and Sjögren's syndrome.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Potential Participants with Systemic lupus erythematosus (SLE)

Inclusions Criteria

Meets definition of SLE diagnosis
Age 18-70
Meets 4 or more ACR formal diagnostic criteria
Anti-dsDNA positive

Exclusion Criteria

Age <18
Has chronic infectious disease
Has cancer and is on chemotherapy
CNS lupus
Drug-induced lupus
Is on IV steroids or cyclophosphamide
Pregnant

Potential Participants with Sjogren’s Syndrome (SjS)

Inclusions Criteria

Age 18-70
Meets American-European Consensus Group classification for primary Sjogren’s Syndrome
Previously established diagnosis of SjS and no other autoimmune connective tissue disease
Positive dry eye signs and symptoms, subjective dry mouth symptoms
Positive test for anti-Ro/SSA and/or anti-La/SSB

Exclusion Criteria

Age <18
Has chronic infectious disease,
Has cancer and on chemotherapy
Is on IV steroids or cyclophosphamide
Pregnant

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Mark Jensen, Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Mark Jensen, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials