A Study Comparing the Outcomes of Observation versus Immediate Surgery for Low Risk Bladder Cancer

Overview

About this study

This trial is a randomized study comparing effectiveness, morbidity, and cost of observation versus immediate surgery for low grade, noninvasive bladder cancer.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

History of low grade, noninvasive urothelial carcinoma of the bladder with a new recurrence that meets the following criteria:
- Total tumor burden ≤ 3cm in size (multiple lesions permitted)
- Low grade appearance (grade 1 or grade 2)
- Noninvasive appearance (Ta)
No history of carcinoma in situ (CIS) or lesions concerning for CIS
Negative urine cytology (atypical or suspicious for low grade neoplasm are acceptable)

Exclusion Criteria

High grade and/or invasive and/or carcinoma in situ disease
Concomitant upper tract urothelial carcinoma
Is pregnant or may have plans to become pregnant
Positive cytology

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Stephen Boorjian, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Stephen Boorjian, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials