A Study to Compare the Effects of Liver Preservation for Transplant via Normothermic Machine Perfusion, versus Static Cold Storage

Overview

About this study

The purpose of this study is to compare the effects of normothermic machine profusion versus static cold storage for preventing preservation-related graft injury in human livers for transplantation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

18 years of age or greater
Registered as an active recipient on the UNOS waiting list for liver transplantation
Subject, or legally authorized representative, is able and willing to give informed consent and HIPAA authorization
Able and willing to comply with all study requirements

Exclusion Criteria

Requires all of the following at the time of transplantation
- Oxygen therapy
- Inotropic support
- Has acute/fulminant liver failure
Is undergoing simultaneous transplantation of more than one organ
Is pregnant or nursing
Concurrent enrollment in another clinical trial.
- Enrollment in clinical trials or registries where only measurements and/or samples are taken (NO TEST DEVICE or TEST DRUG USED) is allowed

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Andrew Singer, M.D., Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Andrew Singer, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials