Clinical Trials

Inclusion Criteria:

• Age ≥18 years.
• Direct face to face contact, within 3 feet, with patients, students, or public as part of full-time (>30 hours/week) job responsibilities.
• K-12 SP with daily face-to-face contact with students throughout the school year.
• Access to medical records:
  • For participants recruited through study sites: HCP, FR and SP who currently and for a minimum of 12 months prior to enrollment receive their medical care through the study site institution as their medical home (either membership in site institution medical plan or part of long-term epidemiologic cohort where medical history and ongoing medical encounter data are captured consistently), and who plan to remain in the area and medical home for the next 12 months (study duration period).
  • For participants recruited through local, regional and national organizations: Willingness to grant access to prior 5 years and current medical records to research staff and ability to access or receive medical records remotely.
• Access to the internet and a phone with text messaging capabilities.
• Willingness to complete twice-weekly symptom assessments via email, phone application or text messaging.
• Willingness to be contacted periodically by study staff via email and telephone.
• Willingness to collect respiratory specimens with nasal swabs when prompted and to package and ship specimens using express mail promptly.
• Willingness to provide blood and serum samples at study enrollment, and again after vaccination and laboratory-confirmed influenza infection/illness, if applicable.

Exclusion Criteria:

• Work less than an average of 30 hours per week.
• Inability to speak or understand English.
• Unwilling to provide verbal and electronic confirmation of consent.
• The individual has previously requested that s/he not be contacted regarding research studies.