Ischemic Preconditioning Prior to Cerebrovascular Interventional Procedures

Overview

About this study

The purpose of this study is to determine if patients receiving Remote ischemic conditioning (RIC) prior to elective endovascular treatment of intracranial aneurysms will have a reduction in rates of cerebral ischemia as detected onimaging when compared to a group of historical controls. Our secondary aim is to determine if patients who receive ischemic preconditioning have any elevation in serum markers for cerebral ischemia.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients who are scheduled to undergo elective intracranial aneurysm treatment using either endosaccular coiling or flow diversion

Exclusion criteria:

History of myocardial infarction within 30 days of the procedure
Age younger than 18 years
Pre-existing ischemic stroke
Pregnancy
Peripheral vascular disease affecting the upper limbs
Upper extremity vascular surgical
Stenting or angioplasty procedures
Patients enrolled in a different trial
Patients requiring radial access
Chronic kidney disease
Current drug therapy with sulfonamide or nicorandil

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator David Kallmes, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

David Kallmes, M.D.

Closed for enrollment

More information

Publications

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Clinical Trials