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Blood and Spinal Fluid Collection for Research Studies in Motor Neuron Disease and Motor Neuropathy

Overview

About this study

The purpose of this study is so that blood (plasma and blood cells) and/or extra spinal fluid (which was taken for clinical purposes) can be obtained and stored for later research on a large cohort of patients with progressive motor neuronopathies and neuropathies, many of which will be determined to suffer from Amyotrophic Lateral Sclerosis (ALS). 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • All patients will have clinically suspected, possible, probable, or definite ALS as defined by the World Federation of Neurology criteria for the diagnosis of ALS (2000).
    • Although some of these patients will later be found to have an ALS “mimicker,” these inclusion criteria will help collect samples all possible patients during their initial laboratory work-up.
  • Age greater than 18 years
  • Can provide written informed consent.

Exclusion Criteria:

  • Patients who are felt to be too ill to complete studies safely

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nathan Staff, M.D., Ph.D.

Open for enrollment

Contact information:

Michelle Turner

(507) 284-1223

Turner.Michelle@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

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CLS-20316346

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