A Study to Improve the Use of Genetic Testing in Disease Prevention and Clinical Care and to Further Understand Types of Genetic Differences that May Cause Disease

Overview

About this study

The purpose of this study is to form processes to get findings from targeted gene sequencing that can be acted on using two common actionable genetic disorders–familial hyperlipidemia and familial colorectal cancer.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

Current participant in the Sangre Por Salud Biobank, Mountain Park Health Center, Phoenix, Arizona (IRB#12-008503)
Dyslipidemia with
- Hypercholesterolemia
  - LDL>140 mg/dL
  - HDL < 40 mg/dL
- Triglycerides >150 mg/dL
- Colon polyps (any type)
Age 18 to 75 years
Resident of Arizona
Able to provide informed consent

Exclusion Criteria

Pregnant females will be allowed to enroll in the study. This is not an interventional study and there will be no risk to the mother or neonate

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Ping Yang, M.D., Ph.D.	Closed-enrolling by invitation What is this? (?) "Close" Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.	Contact information: Noralane Lindor M.D. (480) 301-9692 nlindor@mayo.edu

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Ping Yang, M.D., Ph.D.

Closed-enrolling by invitation

Contact information:

Noralane Lindor M.D.

(480) 301-9692

nlindor@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials