Characterizing the Inflammatory Marker Profiles of Free Flap Reconstructive Head and Neck Surgery

Overview

About this study

The purpose of this study is to characterize the inflammatory markers of free flap reconstructive head and neck surgery in humans by analyzing specific inflammatory markers in blood samples from patients with the hope of better understanding free flap physiology in order to eventually improve patient outcomes.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patient is between ages 18 and 65
Must be undergoing reconstructive head and neck surgery following cancer excision
Patient must be undergoing either a radial forearm free flap, fibular free flap, or scapular system free flap performed by the Otolaryngology-Head and Neck Surgery (Mayo Clinic, RST) department.

Exclusion Criteria:

Anyone who is currently taking immunomodulatory or immunosuppressant medications
Anyone with a history of autoimmune disease
Anyone with a current diagnosis of type II diabetes mellitus or chronic kidney disease
Anyone who is pregnant

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Jeffrey Janus, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Jeffrey Janus, M.D.

Closed for enrollment

More information

Publications

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