Clinical Trials

Inclusion Criteria: 

• Male and females over the age of 18 years.
• Willing and able to give informed consent.
• Diagnosis of ataxia and other nucleotide repeat diseases with genetic mutation and unaffected family members.
• Patients with ataxia and other nucleotide repeat diseases who do not have known family history.
• Males and females over 18 years of age with no known history of cerebellar ataxia or nucleotide repeat diseases will be used as controls.                  

Exclusion Criteria:

• Patients that do not want to participate by either checking no on the contact letter or refusing over the phone. This will be recorded in the Progeny system and patients will not be contacted again.
• Allergy to study-related materials including lidocaine or iodine. We will make all efforts to utilize alternative means when obtaining specimens (i.e. using rubbing alcohol and obtaining blood samples instead of skin biopsies).
• Potential subjects will not be excluded based on being minorities.
• We propose to include 1000 subjects in our repository.