Clinical Trials

Inclusion Criteria:

• Adult (age ≥ 18 years).
• Resuscitated from non-traumatic cardiac arrest (including any arrest rhythm or non-traumatic etiology, including in-hospital and out-of-hospital cardiac arrest) admitted to Mary Brigh 4 D/E CICU.
• Sinus rhythm at the time of enrollment OR underlying atrial fibrillation with a paced rhythm present.

Exclusion Criteria:

• Atrial fibrillation (or other non-sinus rhythm) at the time of enrollment unless a paced rhythm is present.
• Mechanical circulatory support (including intra-aortic balloon pump).
• DNR status.
• Inadequate imaging windows for satisfactory TTE data acquisition.
• Need for inotropic support (any dose of dobutamine, epinephrine, dopamine) or high-dose vasopressors (norepinephrine >0.1 mcg/kg/min or equivalent) at baseline.
• Pregnant women.
• Prisoners
• Secondary exclusion criteria ONLY apply to the DSE sub-study:
  • Atrial or ventricular arrhythmias requiring ongoing intravenous antiarrhythmic drug therapy;
  • Unrevascularized severe CAD or concern for ongoing myocardial ischemia;
  • Clinical judgement by the treating physician that low-dose dobutamine would be harmful;
  • Known sensitivity or allergy to dobutamine.