Clinical Trials

Inclusion Criteria

• CD subjects with symptoms that are attributed by the referring provider to intestinal strictures based on clinical assessment and/or unequivocal enteric luminal narrowing with or without proximal enteric dilatation on cross-sectional imaging (CT or MRI).
• Subjects who are expected to undergo surgical resection of the intestinal strictures.
• Male or female with age greater than 18 years old.
• Subjects with the capacity to give informed consent and willingness to provide a written consent.

Exclusion Criteria

• Subjects requiring emergent surgery for enteric strictures.
• Blood glucose of greater than or equal to 200mg/dL at the time of PET/MRE or if a subject is diabetic and glucose is not controlled. At the discretion of the PI and the authorized user and with their approval prior to FDG injection, subjects with blood glucose ≥ 200 mg/dL may participate in the study.
• Pregnant and/or breast feeding subjects.
• Subject weighing more than the allowable PET/MRE scanner weight limit (245kg).
• Subjects with contraindication to MRI including:
  • Subjects who have a heart pacemaker.
  • Subjects who have a metallic foreign body (metal sliver) in their eye, or who have an aneurysm clip in their brain.
  • Subjects who have implanted devices with magnets.
  • Subjects who have other implanted electronic devices.
  • Subjects who have deep brain stimulator.
  • Subjects who have vagal nerve stimulator.
  • Subjects with cochlear (ear) or auditory implants
• Subjects with history of allergic response to radiocontrast media
• Subjects with known history of claustrophobia.