A Study of Exercise Testing and Assessment for Improving Early Identification of Abnormalities of Fontan Circulation, and Early Diagnosis of Fontan Associated Disease (FAD)

Overview

About this study

The purpose of this study is to:

Define and determine the prevalence of pulmonary vascular disease and diastolic dysfunction as assessed by the gold standard of invasive hemodynamic cardiopulmonary exercise testing.
Determine the role of rest-exercise echocardiography for the assessment hemodynamics in Fontan physiology.
Evaluate the clinical impact of pulmonary vascular disease and ventricular diastolic dysfunction.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

≥18 years
Fontan Palliation
Undergoing clinical cardiac catheterization
Able to exercise
Able to provide informed consent

Exclusion Criteria:

Patients with thrombotic occlusions or inadequate access

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Alexander Egbe, M.B.B.S., M.P.H.	Closed for enrollment	Contact information: Katherine Peterson (507)284-3642 Peterson.Katherine1@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Alexander Egbe, M.B.B.S., M.P.H.

Closed for enrollment

Contact information:

Katherine Peterson

(507)284-3642

Peterson.Katherine1@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials