Clinical Trials

Inclusion Criteria:

• ≥ 18 years of age and be diagnosed with cancer.
• Provide informed consent.
• Ability to complete questionnaire(s) by themselves or with assistance.
• Planned use of one of the defined systemic, antineoplastic therapies.
• Willingness to complete questionnaires with each dose of therapy.
• Plan to receive chemotherapy for the following 3-4 months OR a minimum of 4 cycles of chemotherapy given at intervals of 2 weeks or longer.
• No prior chemotherapy over the previous 3 months.

Exclusion Criteria:

• Predisposition to frequent nosebleeds (more than once per month).
• Verbal baseline nasal dryness, pain, bleeding, or scabbing ≥ 2 on a 10 point scale (from mild=1 to severe=10).
• Planned receipt of two of the studied agents concurrently (e.g., abraxane and bevacizumab).
• Planned participation in a placebo-controlled trial.