Clinical Trials

Inclusion Criteria:

1. Age 18 years or older.
2. Diagnosed by preoperative imaging modalities to have an intracranial vascular lesion (aneurysm, arteriovenous malformation or arteriovenous fistula) or a brain tumor with intimate vascular relationships requiring microsurgical intervention.
3. Patient or legally authorized representative provides written informed consent to enroll in this study.Translation will be provided as appropriate by each institution.
4. Inclusion of women and minorities:Both men and women and members of all ethnic groups are eligible for this trial.

Exclusion Criteria:

1. Known allergic reaction to ICG or to any iodides, as ICG contains sodium iodide.
2. Children, prisoners, and students.
3. Patients who are pregnant.
4. Hemodynamic instability or significant impairments in circulation.
5. Any uncontrolled systemic condition unrelated to the neurosurgical disease.
6. History of psychiatric, additive, or any other disorder that compromises the ability to provide informed consent or comply with study protocols.
7. Participation on other clinical trials during the last thirty days.