Clinical Trials

Inclusion Criteria:

ICU patients who spent over 48 hours in the ICU and met at least one of the following criteria:

• Patient was CAM-ICU positive during ICU stay;
• Need for mechanical ventilation;
• Need for vasopressors;
• Need for acute non-invasive positive pressure ventilation;
• Need for supplemental oxygen via nonrebreather mask, high flow nasal cannula;
• Needed sedation.

Exclusion Criteria:

• Patients with known prior diagnosis of psychotic disorders such as schizophrenia or acute alcohol/substance intoxication/withdrawal.
• Admission for suicide attempt.
• Known prior cognitive impairment or severe Alzheimer’s disease or dementia of any etiology.
• Life expectancy < 3 months.
• Non-English speaking.
• Severe current cognitive impairment (3 or more errors on 6-item cognitive screen) traumatic brain injury.
• Cerebrovascular accidents with resultant moderate to severe cognitive deficits or ADL disability.
• Parkinson’s disease.
• Huntington’s disease.
• Acquired or congenital mental retardation.
• ICU admission post cardiopulmonary resuscitation with suspected anoxic injury.
• Blind.
• Deaf.
• Prisoners.
• Patients who are homeless and have no secondary contact person available.
• Wheelchair bound prior to admission.