Recovery from Cushing syndrome and Mild Autonomous Cortisol Secretion

Overview

About this study

The primary purpose of this study is to determine pre-surgical and post-surgical predictors of the duration and severity of glucocorticoid withdrawal in patients undergoing a curative surgery for cortisol excess.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age 18 years old and above.
New diagnosis of CS of any of the three subtypes (pituitary, adrenal or ectopic CS) and MACS.
Planning for therapy/conservative follow up for CS/MACS
Ability to provide informed consent.

Exclusion Criteria:

Systemic supraphysiological GC for any reason within 1 month of enrollment, and for more than 2 weeks.
Inability to provide informed consent.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 06/12/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Irina Bancos, M.D., M.S.	Open for enrollment	Contact information: Vanessa Fell M.A. (507) 266-6068 Fell.Vanessa@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Irina Bancos, M.D., M.S.

Open for enrollment

Contact information:

Vanessa Fell M.A.

(507) 266-6068

Fell.Vanessa@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials