A Study to Identify Biomarkers in Patients with Rheumatoid Arthritis and Interstitial Lung Disease

Overview

About this study

The purpose of this study is to establish the immunometabolic profile of T cells isolated from patients with Rheumatoid Arthritis/Interstitial Lung Disease (RA/ILD), to identify distinguishing features in the metabolic status of T cells from RA patients with and without ILD, and to explore the use of immunometabolic determinants as a biomarker in RA patients with and without ILD.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients positive for rheumatoid factor and/or anti-CCP antibodies.
Patients with a strong suspicion for coronary artery disease or CAD documented by prior bypass surgery, prior placing of coronary stents or prior documentation of myocardial infarction.
Patients undergoing coronary computed tomography angiography (CTA) for clinical care.
Healthy Controls:
- > 60 years of age;
- No history of cardiovascular disease based on evaluation of a physician.

Exclusion Criteria:

None

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 8/14/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Cornelia Weyand, M.D., Ph.D.	Open for enrollment	Contact information: Emily Oldham (507) 538-7772 Oldham.Emily@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Cornelia Weyand, M.D., Ph.D.

Open for enrollment

Contact information:

Emily Oldham

(507) 538-7772

Oldham.Emily@mayo.edu

More information

Publications

Publications are currently not available

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