A Study to Evaluate Cardiac Magnetic Resonance Elastrography (MRE) of Acute Myocardial Infarcts

Overview

About this study

The purpose of this study is to determine whether cardiac magnetic resonance elastography (MRE) can detect acute myocardial infarctions in humans as areas of increased stiffness, and to compare cardiac MRE stiffness to microvascular obstruction in acute myocardial infarction.  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years old.
  • New myocardial infarction within 10 days of enrollment

Exclusion Criteria:

  • Contraindications to MRI scanning including internal defibrillators or pacemakers, cerebral aneurysm clips, or severe claustrophobia.  
  • Contraindications to gadolinium-based MRI contrast material; namely, glomerular filtration rate less than or equal to 30mL/min. 
  • Patients with no serum creatinine available within 30 days will have a new serum creatinine drawn to calculate glomerular filtration rate. 
  • Women who are pregnant or lactating.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Philip Araoz, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available
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CLS-20475713

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