Clinical Trials

Inclusion Criteria:

Fulminant Myocarditis case definition: (Criteria 1, 2 AND 3, PLUS 1 or more of criteria 4, 5, OR 6 must be met):

1. No evidence of significant valvular heart disease, congenital heart disease, or heart disease secondary to endocrine disorders
2. Onset of heart failure symptoms < 2 weeks prior to diagnosis, requiring at least 1 inotrope or mechanical circulatory support
3. If the patient is ≥40 years, coronary artery imaging by CT, MRI or invasive coronary angiography shows a maximum of one lesion ≥70% in severity
4. EMB positive for borderline or active myocarditis per Dallas criteria.
5. Cardiac MRI positive for myocarditis per Lake Louise criteria.
6. LVEF <50% per cardiac imaging plus elevated troponin in the setting of a compatible clinical scenario

Exclusion Criteria:

1. Patients who are being treated with immunosuppressive therapy at the time of the initial visit will be excluded from the study.
2. Under the age of 18.