Biologic Repository for Esophageal Disease

Overview

About this study

The purpose of this study is to develop a Biobank of blood and tissue collected from individuals with known or suspected Barrett’s esophagus , esophageal adenocarcinoma, squamous dysplasia and carcinoma.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

BE segment will be defined as 2 cm or more of esophageal columnar epithelium, measured from the esophagogastric junction to the highest tongue, with biopsy confirmation of intestinal metaplasia with goblet cells.
Adenocarcinoma of the esophagus will require biopsy confirmation of cancer.
Squamous cell carcinoma of the esophagus will require biopsy confirmation of squamous neoplasia.

Exclusion Criteria:

Age less than 18
Inability to sign a consent (mental retardation, non-English speaker)
Non adeno or squamous cell malignancy (such as a leiomyosarcoma)
Vulnerable population (prisoner)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Jacksonville, Fla. Mayo Clinic principal investigator Herbert Wolfsen, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Jacksonville, Fla.

Mayo Clinic principal investigator

Herbert Wolfsen, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Clinical Trials