A Study of Topical Antibiotics in Chronic Rhinosinusitis

Overview

About this study

The purpose of this study is to describe the results of antibiotic resistant organisms after the use of topical antibiotics in the treatment of chronic rhinosinusitis.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

All participants in the study must meet all of the following inclusion criteria to participate in this study:

Diagnosed with chronic rhinosinusitis who have undergone previous functional endoscopic sinus surgery including at minimum maxillary antrostomy and anterior ethmoidectomy.
Active mucopurulence on endoscopic examination with corresponding culture demonstrating pathogenic bacterial growth.
Completion of written informed consent.
No prior enrollment into this study.
Refractory to maximal medical therapy.

Exclusion Criteria:

Candidates meeting any of the following exclusion criteria at baseline will be excluded from study participation:

Patient has not had prior endoscopic sinus surgery consisting of at minimum bilateral maxillary antrostomy and anterior ethmoidectomy.
Patient is currently being treated with oral antibiotics.
Patient has been treated with oral or topical antibiotics within the past 14 days.
Participation in an investigational drug study simultaneously with participation in this study.
Concurrent use of oral steroids.
Known to currently be pregnant.

More information

Publications

Publications are currently not available

Clinical Trials