A Study to Evaluate 7T Magnetic Resonance Imaging in Multiple Sclerosis

Overview

About this study

The purpose of this study is to compare the effectiveness of 7T imaging to the current conventional imaging (3T) to improve MR sensitivity to the changes of multiple sclerosis. Using FDA-cleared 7T imaging would have a substantial impact on patient management.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥ 18 years old.
Capable of giving consent.
Established diagnosis of Multiple Sclerosis according to McDonald Criteria (2018). Patients may be diagnosed with any of the conventional phases of MS, primary progressive, relapsing remitting, secondary progressive etc.
Willing to participate in a 7T MRI examination within a few days of their clinical 3T or 1.5T examination.

Exclusion Criteria:

Age < 18 years old.
Any metallic implant, device implant, ventriculoperitoneal shunt, cardiac valve, pacemaker which would constitute a contraindication to 7T imaging.
Previous craniotomy.
Permanent facial makeup (for brain scanning).
Suffer from claustrophobia.
Pregnancy.
Fever / elevated temperature.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Padraig Morris, M.B., B.Ch.	Open for enrollment	Contact information: Suson Walsh CCRP (507) 293-0039 Walsh.Suson@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Padraig Morris, M.B., B.Ch.

Open for enrollment

Contact information:

Suson Walsh CCRP

(507) 293-0039

Walsh.Suson@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials