Clinical Trials

Inclusion Criteria:

• Age 18-80 years.
• Recipient of kidney transplantation 4 or 7 years earlier.
• Competent and able to provide written informed consent.
• Ability to comply with protocol.

Exclusion Criteria:

• Patients have clinically significant medical conditions within the prior 6 months before; e.g., myocardial infarction, congestive heart failure, stroke, that would, in the opinion of the investigators, compromise the safety of the patient.
• Severe chronic liver, heart, or lung disease.
• Undergoing acute rejection.
• Contra-indication to biopsy; bleeding disorders.
• Chronic infection.
• Any active malignancy and undergoing therapy.
• Kidney or ureteric stone.
• Unable to give valid informed consent.
• Known pregnancy or intent to conceive during the study period.
• Pacemaker, implantable defibrillator, magnetically active metal fragments, claustrophobia or other contraindication to MRI.
• Federal medical center inmates.
• Latex allergy.

Eligibility last updated 9/9/21. Questions regarding updates should be directed to the study team contact.