A Study to Evaluate the Impact of Automated Zonal Control of Indoor Air Pollutants in a Simulated Apartment

Overview

About this study

The purpose of this study is to understand the health effects of indoor air pollution sources by focusing on controlling emissions from cooking, cleaning, and personal care product use by automating air cleaning devices, exhaust fans, and air handling unit (AHU) supply flow rates based on air quality sensor measurements.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Individuals 25 years of age or over.
  • Individuals with a regular schedule of at least 5 working days a week that are not shift work.
  • Ability to relocate to the Well Living Lab for four weeks (25 nights).
  • Willing to remain in the lab after waking up until all specimens and measures are completed.
  • Ability to fulfill scripted tasks, including cooking and cleaning.
  • Ability to have blood drawn and urine samples collected one time prior to move-in and two times per week for a four-week period.
  • Ability to provide informed consent.

Exclusion Criteria: 

  • Individuals with abnormal blood tests of lipids or biomarkers of liver and kidney dysfunction.
  • Individuals who are smokers or having quit smoking <1 year prior.
  • Individuals who have a respiratory infection.
  • Individuals who have signs and symptoms of obstructive pulmonary disease, asthma, heart failure or cardiac arrhythmia.
  • Individuals who use corticosteroids, anti-arrhythmic medication, beta-blockers, anti-inflammatory drugs or aspirin.
  • Individuals who have occupations with increased air pollution exposure.
  • Women who are pregnant or intend to become pregnant during the duration of the study.
  • Women who are experiencing menopausal transition.
  • Individuals with a history of mood or psychiatric disorders.

Individuals who perform shift work.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available
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CLS-20502004

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