A Study to Evaluate Deep Venous Thrombus Characteristics and Venous Dynamics with Subsequent Thrombus Resolution and Post-thrombotic Syndrome

Overview

About this study

The purpose of this study is to complete the following aims:

Aim 1: Evaluate initial thrombus characteristics by ultrasound (US) shear wave elastography (SWE) in acute, proximal, deep venous thrombus (DVT).

Aim 2: Prospectively evaluate the role of venous hemodynamics on acute proximal DVT resolution and post-thrombotic syndrome (PTS).

Aim 3: Examine biomarkers of coagulation as predictors of acute proximal DVT resolution and PTS.

Aim 4: Expand the scope of the Mayo Clinic VTE registry to include high quality outcome data on post-thrombotic syndrome.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

- Diagnosis of acute, proximal (popliteal and above) DVT with or without Pulmonary
Embolism within 72 hours

- ≥18 Years Old

Exclusion Criteria

- prior episode of DVT

- contraindication to standard therapeutic anticoagulation

Eligibility last updated 7/11/22. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Damon Houghton, M.D., M.S.

Closed for enrollment

Contact information:

Brakha Tabi Zerbib

(507) 266-5179

Tabi.Brakha@mayo.edu

More information

Publications

Publications are currently not available
.
CLS-20503208

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