Clinical Trials

Inclusion Criteria:

• Obesity (BMI > 30 kg/m^2).
• Mayo Clinic patients evaluated by Dr. Rahul Pannala.
• Equal distribution of gender.
• ≥ 18 years of age.
• BMI > 30 kg/m^2.
• Nonsmoker.
• Taking no medication affecting glucose or lipid metabolism.
• No more than 5% change in body weight in the previous 6 months.
• Mostly sedentary (engaging in strenuous exercise (> 70% max HR) less than 3 times a week).
• Not be receiving corticosteroid therapy.
• Have no history of asthma, COPD or atopic syndrome, or autoimmune disease (ulcerative colitis, Chrohn’s disease, eosinophilic esophagitis, any rheumatologic disease such as lupus, rheumatoid arthritis, Sjogren's syndrome).

Exclusion Criteria:

• < 17 years of age.
• BMI < 30 kg/m^2.
• Smoker.
• Taking medication affecting glucose or lipid metabolism.
• Greater than 5% change in body weight within the previous six months.
• Engage in strenuous exercise (> 70% max HR) or more than 3 times a week.
• Receiving corticosteroid therapy.
• History of severe asthma on chronic steroid therapy.
• History of COPD or atopic syndrome.
• History of autoimmune disease (ulcerative colitis, Chrohn’s disease, eosinophilic esophagitis, any rheumatologic disease such as lupus, rheumatoid arthritis, Sjogren's syndrome).

Eligibility last updated 8/12/21.  Questions regarding updates should be directed to the study team contact.