A Study to Assess Outcome of Hospitalization for Cirrhosis Patients

Overview

About this study

The purpose of this study is to evaluate the outcome of hospitalization related to the presence of cirrhosis. We are participating in optional blood, saliva, urine, ascitic fluid and stool collection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age ≥ 18 years.
Cirrhosis or chronic liver disease (defined as FIB-4 > 1.45 or other non-invasive markers that show > F3 fibrosis on outpatient values).
Admitted for non-elective reasons.
Able to consent or have a legal representative who can consent.

Exclusion Criteria:

Individuals < 18 years of age.
Acute liver failure.
Unable to consent.
Admitted electively.
Life expectancy < 48 hours.
Prisoners.
HCC without loco-regional control for > 6 months or patients on systemic therapy for Hepatocellular Carcinoma (HCC) currently.
COVID-19 diagnosis confirmed during the current admission.
Post-TIPS if TIPS is > 6 months prior.
Known recent MI (< 6 months) or stroke with residual defects.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Jody Olson, M.D.	Open for enrollment	Contact information: Amy Olofson R.N. (507) 538-6547 Olofson.Amy@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Andrew Keaveny, M.D.	Closed for enrollment	Contact information: Andrew Keaveny M.D. (904) 956-3200 Keaveny.Andrew@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Hugo Vargas, M.D.	Open for enrollment	Contact information: Hugo Vargas M.D. (480) 301-6990 Vargas.Hugo@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jody Olson, M.D.

Open for enrollment

Contact information:

Amy Olofson R.N.

(507) 538-6547

Olofson.Amy@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Andrew Keaveny, M.D.

Closed for enrollment

Contact information:

Andrew Keaveny M.D.

(904) 956-3200

Keaveny.Andrew@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Hugo Vargas, M.D.

Open for enrollment

Contact information:

Hugo Vargas M.D.

(480) 301-6990

Vargas.Hugo@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials