Mayo MRI White-Matter-Nulled Imaging Study

Overview

About this study

The purpose of this MRI calibration study is to determine usability and optimize functionality of the MRI acquisition and post-processing techniques for white matter null imaging.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Provision of signed and dated informed consent form.
  • Stated willingness to comply with all study procedures and availability for the duration of the study.
  • Male or female, 18 years of age or older.
  • In good general health as evidenced by medical history but may include a diagnosis of epilepsy.
  • Volunteers who are confirmed to have temporal lobe epilepsy based on established medical history and have established outpatient epilepsy care within the Mayo Clinic Health System.

Exclusion Criteria:

  • Participants with a contraindication to MRI. Such contraindications include, but are not limited to: pacemaker, metallic cardiac valve(s), magnetic material such as surgical clips, tattoos, implanted electronic infusion pumps or any other condition that would interfere with the MRI, a stent somewhere in the body, a history of allergic reaction to any metals.
  • Participants who have structural anatomical legions outside the medial temporal lobe.
  • Pregnancy or lactation.
  • Participants who report previous experience with claustrophobia, anxiety and/or vertigo when moved inside the scanner.
  • Febrile illness within the last thirty days.
  • Treatment with another investigational drug or other intervention within the last thirty days.
  • Subjects incapable of giving informed written consent.
  •  Participants in the prisoner population.

Eligibility last updated 8/26/21. Questions regarding updates should be directed to the study team contact.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Gregory Worrell, M.D., Ph.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Jodi Silvernail

(507) 284-1686

Silvernail.Jodi2@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20521079

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