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Analysis of Fast Atrial Rhythm Manifesting with Increased Urination

Overview

About this study

The objective of this study is to investigate this phenomenon by identifying such patients and analyze this relationship using biomarkers (blood and urine signal proteins) related to volume control such as pro-atrial natriuretic peptide (pro-ANP), N-terminal B-type natriuretic peptide (NT-proBNP), cyclic-GMP (a downstream second messenger for natriuretic peptides) and copeptin (the pre-pro-hormone of antidiuretic hormone).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 18 or older.
  • Patients with paroxysmal atrial tachyarrhythmias with and without polyuria as a manifestation of their tachyarrhythmia episode.
  • Documentation of their paroxysmal atrial tachyarrhythmia episode.

Exclusion Criteria:

  • Patients who are unable to manage the logistics of participating in the study (coming to Saint Mary’s Hospital ot have their blood drawn and urine sample collected during their atrial tachyarrhythmia episode).
  • Chronic kidney disease stage 4 or higher.
  • Clinical history of heart failure.

Eligibility last updated 10/1/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Allan Jaffe, M.D.

Closed-enrolling by invitation

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"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Ronstan Lobo M.B., B.Ch., B.A.O.

(507) 284-8586

Lobo.Ronstan@mayo.edu

More information

Publications

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