Clinical Trials

Inclusion Criteria:

• Female patients age 18 at the time of signing informed consent, up to 55 years of age.
• Ultrasound confirmation of twin pregnancy no later than 20 weeks gestational age (GA), and prior to Panorama.
• Panorama planned no later than 20 weeks GA.
• Willing and able to provide written informed consent.
• Willing and able to comply with institution’s standard of care prenatal procedures, including ultrasound assessments and Panorama.
  • Note: subjects with known major congenital anomalies, known unbalanced chromosomal complement or ruptured membranes, may be enrolled in the study.

Exclusion Criteria:

• Singleton or non-twin multiple pregnancy.
• Ultrasound confirmation of twin pregnancy at 20 weeks 1 day GA or later.
• Patient has received a Panorama test and the enrolling physician has received the Panorama test results prior to any ultrasound assessment of chorionicity & amnionicity.
• Panorama testing is planned at 20 weeks 1 day GA or later.
• Any confounding complication or condition that, in the opinion of the investigators, precludes participation in the study, such as evidence of TTTS or other monochorionic pregnancy complication already at the time of enrollment.
• Unwilling or unable to participate in the institution’s standard of care prenatal ultrasound and/or testing with Panorama.
• Unwilling or unable to provide written informed consent.

Eligibility last updated 4/26/22. Questions regarding updates should be directed to the study team contact.