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Immune Aging

Overview

About this study

The objective of this study is to identify immune defects that compromise the immune response with age.  As humans age, vaccinations become less effective. Vaccines are only partially protective or not protective at all in older populations. Preventing or compensating these defects may improve immune responses in the elderly.

 

 

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults, ≥ 18 years of age.

Exclusion Criteria:

  • Individuals under 18 years of age.
  • History of chemotherapy for malignancies.
  • Immunosuppressive therapy for autoimmune disease.
  • Chronic comorbidities not controlled on medication.
  • Acute infectious disease.
  • Pregnancy.

Eligibility last updated 4/25/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jorg Goronzy, M.D., Ph.D.

Open for enrollment

Contact information:

Patricia Kennedy

(507) 266-1986

Kennedy.Patricia1@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

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CLS-20526390

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