A Study to Establish a Research Tissue Bank for Myeloproliferative Neoplasms

Overview

About this study

The purpose of this study is to credential novel therapeutic approaches which can then be transitioned to the clinic for near-term mechanism based clinical trials in this research consortium. There is a need for new treatments for myelofibrosis (MF) patients based on laboratory insight into disease pathogenesis. We will use primary patient samples to understand how different genetic mutations contribute to MF development and to test novel treatment approaches.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria - Eligible patients must meet criteria 1 OR 2:

Newly diagnosed subjects diagnosed with Philadelphia chromosome negative myeloproliferative neoplasms (MPN) polycythemia vera (PV), prefibrotic myelofibrosis (Pre-PMF), overt primary myelofibrosis (PMF), essential thrombocythemia (ET), and myeloproliferative neoplasm blast phase (MPN-blast phase) or MPN-Unclassifiable (MPN-U).
Patients previously treated for an MPN.
Signed informed consent is required from each patient at the time of enrollment.

Exclusion Criteria:

Patients currently participating in experimental treatment arms of MPN-RC protocols, or other experimental treatment protocols.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Jeanne Palmer, M.D.	Open for enrollment	Contact information: Cancer Center Clinical Trials Referral Office 855-776-0015

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Jeanne Palmer, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

855-776-0015

More information

Publications

Publications are currently not available

Clinical Trials