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Metabolism-informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

Overview

About this study

This present effort is the first step of a larger study. We are limiting the scope this AAIRB application to only the first step. The goal of the overall research study is to examine the acceptability and feasibility of using NMR to inform selection of pharmacologic treatment to increase smoking abstinence among ANAI people.

The aim of this IRB application (Aim 1a) is to refine a metabolism-informed pharmacologic intervention to optimize design and participation of a future pilot.

We will use a community-based participatory research (CBPR) approach with ANAI customer-owners, providers, and leaders to refine intervention materials and protocols used by Wells et al. for use in an ANAI clinical environment. By eliciting feedback on the acceptability and feasibility of components of the intervention through interviews, we will be able to refine the design of the intervention and future pilot.

Then, in a future AAIRB application, we will use rapid-cycle methods to beta-test the intervention with 10 customer-owners to further optimize the intervention (Aim 1b). In a third and final AAIRB application pertaining to this study, we will assess the refined intervention in a single-arm pilot (Aim 2). The current IRB application (Aim 1a) is only to conduct interviews to refine an NMR intervention and pilot design.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Customer-owner: ANAI person by self-report; eligible for or already receiving services at SCF; age 18 years or older; daily smoking in the past 30-days; cigarettes are main tobacco product used; willing to make a quit attempt; and has phone service.  Note that attempting to quit tobacco is not required for participation. Rather the goal of this criterion is not to include individuals that are pre-contemplative to quitting tobacco. Individuals with questionable capacity or impaired decision-making capacity are not being sought for participation.
  • Provider: Participants must be age 18 years or older and a health care professional at SCF including but not limited to primary care providers, behavioral health consultants, tobacco treatment specialists, pharmacy providers, and psychiatrists. 
  • Leaders: Participants must be age 18 years or older and tribal, administrative, or clinical leaders engaged in the design, delivery, and operation of the SCF health care system; must be employed by—or have otherwise engaged in a substantive manner with—SCF for the past 2 years, including but not limited to data services staff, clinical directors, administrators of primary and behavioral health care services, and individuals in executive roles.

Exclusion Criteria:

  • Any exclusion to criteria above.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Christi Patten, Ph.D.

Contact us for the latest status

Contact information:

Nicole Reinicke M.B.A.

(907) 729-8623

Reinicke.Nicole@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20530002

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