Clinical Trials

Inclusion Criteria:

• Southeast Minnesota (SEMN, covering MCR and MCHS vicinities), Southwest Wisconsin (SWWI, covering MCR and MCHS vicinities), Florida (covering Jacksonville FL region) and Arizona (covering Scottsdale AZ region) residents (residency established at least one year prior to consent).
• Aged 18- 64 years at the time of consenting.
• Those who have primary care physician at Mayo Clinic and had at least one visit to one of Mayo Clinic sites within 3 years prior to the study index date.
• Those who authorize use of their medical record for research (MN only).
• Those who provide written consent to participate in the study.

Exclusion Criteria:

• Subjects without authorization for use of medical records for research.
• Those who do not reside in catchment areas served by MCR/MCHS, MCF, and MCA.
• Those who receive primary care at a non-Mayo medical facility.
• Those who develop ARI after October 1st, 2022, if consent is done between October 1st, 2022, and November 30th, 2022.
• Those who refuse swab test.
• Those who cannot ambulate or those who are bedridden.
• Those with known cognitive impairment.
• Those who reside out of their resident counties > 2 weeks during winter season (Oct-April) and/or >4 weeks during summer season (May-Sep).