Non-Invasive Positive Pressure Ventilation on Oxygen Saturations without Supplemental Oxygen at Altitude

Overview

About this study

The purpose of this study is to assess changes in cognitive function and physiological signs that may be affected at General Aviation altitudes considered safe by the Federal Aviation Administration; and whether these affects can be mitigated by through the use of a simple non-invasive positive pressure device.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Healthy male or female participants.
Between the ages of 18 and 89.
Must have had experience as a pilot or passenger in an unpressurized general aviation aircraft at altitudes above 8,000 feet and have not experienced any serious adverse effects from this experience (such as serious vertigo, loss of consciousness, any cardiac or respiratory dysfunction, or any other illness requiring medical treatment).
Participants need to be able to complete cognitive tests.
Must be fluent in English.

Exclusion Criteria:

Patients < 18 years of age or > 89 years of age.
Pregnant women.
Unable to read and speak English.
History of Cardiac disease, Pulmonary disease, Cerebrovascular disease, Neurological disease, Vertigo, or Syncope.
Any documented incidences of Serious Adverse effects from General Aviation.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Bruce Johnson, Ph.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Closed for enrollment

More information

Publications

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