Facet Joint Articular Cartilage and Disc and Endplate Cartilage Healthy and Degenerated Characterization

Overview

About this study

The purpose of this study is to determine the biomechanical, biochemical, and histological properties of human spinal cartilage, in both healthy and degenerated patients, and to compare the properties among the different regions of the spine (cervical, thoracic, and lumbar).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

All adult patients ≥ 18 years of age.
Undergoing spinal fusion surgery in which the facet articular cartilage or disc and endplate cartilage is removed and discarded to allow for spinal fusion. Cervical, thoracic, and lumbar.

Exclusion Criteria:

< 18 years of age.

Eligibility last updated 9/19/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Benjamin Elder, M.D., Ph.D.	Open for enrollment	Contact information: Kiersten Sydnor (507) 255-9846 Sydnor.Kiersten@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Benjamin Elder, M.D., Ph.D.

Open for enrollment

Contact information:

Kiersten Sydnor

(507) 255-9846

Sydnor.Kiersten@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials