Clinical Trials

Inclusion Criteria - normal first trimester pregnancy tampon group: 

• Viable intrauterine pregnancy on ultrasound.
• < 15 weeks gestation.

Inclusion Criteria - surgical D&C group:

• Confirmed non-viable missed miscarriage or incomplete miscarriage (also termed missed abortion/incomplete abortion) and planned dilation and curettage or manual vacuum aspiration procedure to remove contents.

Inclusion Criteria - ectopic/suspected ectopic with pregnancy of unknown location:

• Clinician identification of suspicious adnexal mass OR abnormally trending hcg level with clinician suspicion for ectopic pregnancy OR surgical listing for ectopic pregnancy.

Inclusion Criteria - control hysterectomy group:

• Age ≤ 42 years undergoing hysterectomy with salpingectomy for prolapse, dysmenorrhea, pelvic pain, non-submucosal fibroids, endometriosis, or gender dysphoria.

Inclusion Criteria - whole peripheral blood group:

• Reproductive age (Age ≤ 42 years), female biologic sex. This group has been previously recruited, samples have been obtained, and is for comparison only.

Exclusion Criteria: 

• Not pregnant.
• Submucosal myoma, current known endometrial pathology (polyp, EIN), IUD in place in preceding month, cervical dysplasia.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 9/6/23. Questions regarding updates should be directed to the study team contact.