Calibrating Laboratory Machinery to Handle Smaller Volumes of Aqueous Humor Samples

Overview

About this study

The purpose of this study is :to calibrate laboratory machinery to handle smaller volumes of ocular tissue samples (aqueous humor) and, ultimately, to compare the biomarkers present in such fluids between those with age-related macular degeneration (AMD) and those without AMD.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients consented for cataract surgery or intraocular lens surgery.

Exclusion Criteria:

  • Patient unable to understand the consent for specimen collection or unwilling to participate.
  • Patients undergoing an intraocular surgery that does not involve corneal paracentesis wound formation.
  • Patients who have ever received intravitreal injections at any prior timepoint.
  • Patients with advanced glaucoma, active uveitis, active choroidal neovascular membrane, proliferative diabetic retinopathy, optic neuropathy, any inherited retinal degeneration, or toxic maculopathy.
  • Patients younger than 18 years old.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 3/20/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Brittni Scruggs, M.D., Ph.D.

Open for enrollment

Contact information:

Suzanne Wernimont CCRP

(507) 538-8119

Wernimont.Suzanne@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20550037

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