Find trials
Search tips

Therapy Targeting Urinary Microbiome Sequencing

Overview

About this study

The purpose of this study is to assess the ability of advanced molecular techniques to identify resistance to antibiotics in human urine and kidney stone samples compared to the gold standard of culture with sensitivities, with a view toward future targeted therapy.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years.
  • Able to provide informed consent.
  • Planned endourologic procedure for upper tract urinary stones (ureteroscopy or percutaneous nephrolithotomy).
  • Able to provide urine sample within 30 days pre-operatively.

Exclusion Criteria:

  • Age ≤ 18 years.
  • Pregnancy.
  • Urinary diversion or previous surgery involving segments of bowel interposed into the urinary tract (ileal conduit, ileal ureter etc.).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/9/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Karen Stern, M.D.

Open for enrollment

Contact information:

Alexis Baughman

(480) 574-2901

Baughman.Alexis@mayo.edu

More information

Publications

Publications are currently not available

More about research at Mayo Clinic

.
CLS-20557345

Mayo Clinic Footer