The KAPP-Sen Tissue Mapping Center Collaborative

Overview

About this study

The purpose of the KAPP-Sen Tissue Mapping Center (TMC) Collaborative is an effort to characterize cellular senescence (cellular aging) in terms of its presence and heterogeneity in healthy human tissues, as well as its tissue burden, spatial distribution, and biological features. This multi-site initiative aims to collect tissue samples from across the US in order to contribute to a repository that aims to support broader knowledge of cellular senescence along with exploring the presence of qualitative and quantitative differences between various tissues, between individuals of the same age and sex, as well as differences between individuals of different ages, racial and ethnic backgrounds, and sex.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Adult donors aged 18 years and older who are scheduled for a clinically planned kidney donation surgical procedure at Brigham and Women's Hospital or UT San Antonio Medical Center.
Adult recipients aged 18 years and older who are scheduled for a clinically planned kidney transplant surgical procedure at Brigham and Women's Hospital or UT San Antonio Medical Center.

Exclusion Criteria:

Adults on anticoagulants

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/17/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Vesna Garovic, M.D., Ph.D.	Open for enrollment	Contact information: Bridget Schley (507) 538-7968 Schley.Bridget@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vesna Garovic, M.D., Ph.D.

Open for enrollment

Contact information:

Bridget Schley

(507) 538-7968

Schley.Bridget@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials