Sugar Hyperabsorption Impact on Post-Bariatric Surgery Weight Loss Outcomes in African American Patients

Overview

About this study

The purpose of this study is to investigate glucose and fructose absorption in enteroids from obese African American subjects before and 1-year post-bariatric surgery compared to age and sex-matched enteroids from obese Caucasian and Hispanic subjects (controls). Also, to profile the expression of glucose and fructose transporters and gluconeogenic enzymes in intestinal tissue from obese African American subjects and compare it to obese Caucasian and Hispanic subjects pre- and post-bariatric surgery.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients aged 18 years or over.
Patientd with class 2 (BMI 35-39.9 kg/m^2) or class 3 (BMI ≥ 40 kg/m^2) obesity.
Patients scheduled for bariatric surgery.

Exclusion Criteria:

Patients under the age of 18.
Patients who are pregnant or breastfeeding women (verified clinically prior to surgery).
Patients with serious comorbidities that may affect surgery outcomes or weight loss.
Patients unable or unwilling to undergo the necessary follow-up evaluations will be excluded from the study.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 8/21/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla. Mayo Clinic principal investigator Dilhana Badurdeen, M.B.B.S., M.D.	Open for enrollment	Contact information: Dilhana Badurdeen M.B.B.S., M.D. Badurdeen.Dilhana@mayo.edu

Mayo Clinic Location

Status

Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Dilhana Badurdeen, M.B.B.S., M.D.

Open for enrollment

Contact information:

Dilhana Badurdeen M.B.B.S., M.D.

Badurdeen.Dilhana@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials